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Gut peptide and neuroendocrine regulation of hepatic lipid and lipoprotein metabolism in health and disease

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do not vortex or shake vigorously, as this can denature peptide bonds

However, the mechanism for induction of ALS neuropathology by statins may be related to the dysregulation of liver X receptor signaling (LXR) signaling in the motor neurons and reduction of cholesterol, which has a neuroprotective effect against ALS neuropathology

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