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Seattle: University of Washington, Seattle

D.WhitworthR.KostenT.RyanN

Under different stimulations, macrophages can be polarized into different subtypes, including broad categories: pro-inflammatory (M1) macrophages and alternative anti-inflammatory (M2) macrophages (48)

In contrast, under acute administration, even when the dose exceeds 4 mg/kg, it only reduces liver weight without improving hepatic morphology or lipid accumulation