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Exenatide and lixisenatide are primarily cleared through the kidneys, while liraglutide, dulaglutide, semaglutide, and tirzepatide undergo proteolytic degradation throughout the body with minimal renal excretion of intact drug
Scheme 4
Supplementation of 15-30 mg of elemental zinc daily is commonly recommended during active weight loss, but should be balanced with copper intake (1-2 mg daily) because long-term zinc supplementation can deplete copper stores
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