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Those who did not discontinue treatment and were on high maintenance dosage of the medications lost 13.7% of their body weight with semaglutide and 18.0% with tirzepatide

There is good reason to expect that similar food/drug reward suppressing effects would be obtained in human subjects since most beneficial effects of GLP-1 reported to date are easily translated from preclinical to clinical studies

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Aging (Albany NY) 2021, 13, (7), 1077010795, Sandusky-Beltran, L

Likewise, it induces beneficial effects on other tissues (i.e., advanced healing of tendons and muscle, recovery of liver cirrhosis, and counteraction of portal hypertension) (see Section 2.1, Section 2.2 and Section 2.3)