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110,111,112 Therefore, NAD(P) + /NAD(P)H represents the switching hub that controls prooxidant-antioxidant balance and determines the redox biology (Fig

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Topological analysis identified the top 10 key targets: IL1B, IL6, TNF, AKT1, CASP3, MAPK3, BCL2, TGFB1, MMP9, and PPARG

This is due to a wide variance in supplementation duration (single dose pre-exercise through to 4 weeks daily supplementation), training status of participants, the implementation of dietary or exercise controls before testing, and the actual exercise test used/ outcome measured

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