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measured MMP1, MMP2, TIMP1, and TIMP2 gene expression in human adult dermal fibroblasts exposed to GHK-Cu at 0.01, 1, and 100 nanomolar concentrations and found dose-dependent increases in both MMPs and their inhibitors 11
Topical dutasteride is available only through compounding, typically at concentrations of 0.01% to 0.1%
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Badenhorst T, Svirskis D, Merrilees M, Bolke L, Wu Z
This is probably the biggest safety concern
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