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Along the same lines as ivacaftor and hypertonic saline, several pharmaceutical groups have been pursuing pharmaceuticals that target other ion channels to improve mucociliary clearance in a cftr -independent manner

Join us at the virtual launch event in a webinar hosted by WHO in collaboration with the Journal of the American Medical Association (JAMA) on 1 December 2025 at 16:00 CET

They found that treatment with metformin in combination with GIMM resulted in lower fasting glucose levels, suggesting better tolerance of metformin therapy for longer or at a higher dosage

WST-1 and caspase assays were performed according to manufacturers instructions

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When you are not hungry, not eating for 24 hours does not feel like deprivation