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Benedetti F, Aggio V, Pratesi ML, Greco G, Furlan R

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Reported Effects Mild and infrequent effects reported in research include transient nasal irritation (intranasal administration), mild headache, and short-lived changes in alertness

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Dietary adjustments often provide significant relief, including eating smaller, more frequent meals rather than large portions, avoiding high-fat or spicy foods that may exacerbate symptoms, and eating slowly to allow for better digestion

Tsukuda, Journal of the American Chemical Society 127, (2005) 52615270