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In UK practice, monitoring is primarily based on clinical response rather than routine blood tests, as post-treatment serum B12 measurements can be misleadingly high and may not reflect tissue levels

Zhang Y, Roh YJ, Han SJ, Park I, Lee HM, Ok YS, Lee BC, Lee S (2020) Role of selenoproteins in redox regulation of signaling and the antioxidant system: a review

This area commonly referred to as Chemistry, Manufacturing and Controls (CMC) plays a key role in ensuring consistency and reliability throughout the study

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Br J Cancer 1999;81(7):12381242