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How providers apply that distinction is a clinical decision made for individual patients

Efficacy and safety of reta, a novel GLP-1, GIP, and glucagon receptor agonist for obesity treatment: A systematic review and meta-analysis of randomized controlled trials

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If you are starting both at once, your provider may begin one first so you can tell which medication is responsible for any side effects, and so two new sources of nausea do not arrive together

Each persons unique medical history and medication regimen may require different precautions to be taken, so its important to discuss with a professional. Editor Lindsay Donaldson contributed to this article

With significant caloric restriction, studies show the body may reduce conversion of thyroid hormone T4 to the more active T3 form and alter sympathetic nervous system activity, both of which can influence heat production