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The mass spectrometry proteomics data have been deposited to the ProteomeXchange Consortium via the PRIDE partner repository (proteomexchange.org) with the data set identifier PXD036803 ( The mass spectrometry metabolomics data (2 data sets from kidney and plasma, respectively) have been deposited to the Zenodo repository ( All reagents, softwares, mouse lines, and data repository information are available in Supplemental Table 7
Research published in peptide patent literature from Diagen indicates the arginate form can achieve oral bioavailability exceeding 90%, compared to less than 3% for the acetate form
Reduced Inflammation: This peptide has potent anti-inflammatory properties, which help minimize swelling and inflammation in injured or damaged areas
PET imaging studies in drug abuse
TCM counteracts this axis by activating AMPK, enhancing energy homeostasis and reducing lipid peroxidation (Li et al., 2015