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Genome expression is operated by Yap1-8 transcription factors, which have the ability to act as both inducers and repressors
GPER mitigates endothelial damage by regulating calcium signaling, the PI3K/AKT pathway, and the MAPK pathway, thereby bolstering antioxidant and anti-inflammatory capacities [192]
533 Metformin also modulates immune responses in lupus and RA
Rzany B, Mockenhaupt M, Baur S, Schroder W, Stocker U, Mueller J, Hollander N, Bruppacher R, Schopf E (1996) Epidemiology of erythema exsudativum multiforme majus, Stevens-Johnson syndrome, and toxic epidermal necrolysis in Germany (19901992): structure and results of a population-based registry
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