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2019;31:e12664

Around the period of Earth's transition from anaerobic to aerobic conditions about 2.4 billion years ago (bya), the evolution of SOD enzymes crucially allowed organisms to overcome the effects of oxidative stress following the surge of molecular oxygen (O 2 ) in the atmosphere (Miller 2012)

2015;8(Spec Issue):43-46.

At present, there are no specific laboratory tests that can confirm the disorder, so the characterization of ASD is basically done by clinical observation associated with the application of specific diagnostic criteria [10,11]

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When these wastes are not neutralized by anti-oxidants such as glutathione, they can lead to chronic diseases such as cancer and autoimmune diseases