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4b, Supplementary Fig

The anti-angiogenic effects of MEL were demonstrated in HepG2 liver cancer cell cultures (239), in which MEL at a concentration of 1 mM was shown to reduce both cellular and secreted VEGF levels and prevent hypoxia-induced tube formation of HUVECs that was associated with decreased Hif1 protein expression, nuclear localization and transcriptional activity

[...] GLP-1 drugs offer non-surgical weight loss, while bariatric surgery provides lasting metabolic changeswe break down which option suits different needs

The onset of meaningful weight loss was slightly faster than semaglutide, with approximately 15% reduction by week 24

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3j), collectively indicating that lipid accumulation potentially results from defective FAO