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Moreover, the variability of data obtained with this technique may be substantial and exceed 10% within and between samples (Aubert et al., Concluding, although many innovative technological approaches were developed to measure TL, there still are substantial inter-laboratory variations and the results obtained by one method can substantially differ from those obtained by other which makes it difficult to use them in epidemiological and clinical studies (Dagnall et al., 2019)

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Heightened inflammation: Dysregulated NF-kB pathways promote pro-inflammatory cytokines