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Patients were excluded if they had K-L grades of 0 or 4, diabetic vascular disease, secondary OA or a history of diabetic foot or knee surgery

The two interact in different parts of the collagen pathway Vitamin C as an enzymatic cofactor, GHK-Cu as a signaling input

The duration of treatment must be long enough to eliminate fecal excretion of the organism, prevent the chance of relapse, and reduce the chance of resistance developing