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Indeed, liraglutide is thought to acutely suppress food intake by activating GABAergic GLP-1R-expressing DMH neurons which project to and inhibit ARC AgRP/NPY neurons as determined by patch-clamp electrophysiology experiments on hypothalamic slices [129]
A Placebo-Controlled Trial of Subcutaneous Semaglutide in Nonalcoholic Steatohepatitis Newsome PN, Buchholtz K, Cusi K, et al
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Insulin detemir: from concept to clinical experience
The majority (57.9%) of all participants had an HbA 1C level below 7.0% (53 mmol/mol) at EOS