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3.8.3 Glyphosate Glyphosate is a widely used herbicide acting via inhibition of the enzyme 5-enolpyruvylshikimate-3-phosphate synthase, which blocks the shikimate pathway responsible for synthesizing aromatic amino acids including phenylalanine, tyrosine and tryptophan (Chiantia et al., 2025)

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Importantly, pre-administration of LASSS to mice prevented the disuse-induced HGF nitration observed in a tail-suspension model for muscle atrophy, while GSSSG did not