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Mechanistic and Translational Research Further investigation into the molecular mechanisms of action could help optimize clinical applications and identify novel therapeutic targets

We therefore understand commenters' concern that having two patient surveys for ASCs would likely result in the potential for low response rates and survey fatigue, even if ASCs provided multiple outreach attempts

In addition, accessory proteins such as COQ4, COQ8A/B, COQ9 and COQ10A/B are believed to facilitate enzyme complex assembly, substrate channeling or stabilization of the biosynthetic complex (commonly referred to as the CoQ synthome) but their precise molecular functions are still under investigation

doi: 10.1016/j.vph.2005.08.028

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