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On March 31st, 2022, the FDA denied the NPA petition as well as another one submitted by the Council for Responsible Nutrition (CRN)

The endothelial solute CMT facilitates the crossing of specific solutes across the BBB via substrate-specific transporters, with docosahexaenoic acid (DHA) being transported by major facilitator superfamily domain containing 2a (Mfsd2a) and glucose by glucose transporter 1 (Glut1), ensuring targeted delivery of these vital nutrients to the brain [19, 24,25,26,27]

PMID: 25983581

Robert et al., 2015)

Tovaru S, Parlatescu I, Tovaru M, Cionca L

3cg, preliminary analyses demonstrated in each case that the interaction between treatment and the dependent variable was not significant, so the interaction term was omitted