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LUPKIN: Yeah, sure

Some people notice benefits like improved hydration, energy, or mental clarity the same day

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So I think theres a concern here that, if you start prescribing this, for addiction that there will be a point in which when theyre no longer on the a, the medications that their cravings for cocaine or alcohol or heroin, you name it will return and thats a concern because if you have stopped using a substance as powerful as heroin for a period of time and then you end up going back to it, then your tolerance is much reduced and your risk of overdose is much, much higher

Roshini Raj, a New York gastroenterologist, said on TODAY

If tirzepatide is something you are curious about or already navigating, talking with a provider who has the time and the background to work through it properly makes a real difference