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SEPS1 contributes to the removal and transfer (retrotranslocation) of misfolded proteins from the ER lumen to the cytosol where proteins are tagged with ubiquitin before being degraded

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Overall, these results show that a 3-month clinical intervention with L-GSH supplementation in T2DM subjects resulted in significantly decreased levels of the proinflammatory cytokine IL-6, and a decrease in the oxidative stress marker MDA

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Foxo-regulated oser1 reduces oxidative stress and extends lifespan in multiple species