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Most of it is lost during digestion, meaning you may see very little change in your actual cellular levels

Cells were pretreated with Gem for 48 h, then treated with Era2 in medium containing 13 C-serine

DEHP with its long side chain is among the most difficult to be utilized phthalates 11

Phase 3 Update: TRIUMPH-4 Results Preliminary data from the ongoing Phase 3 TRIUMPH-4 trial (68 weeks) shows higher numbers than Phase 2: 12mg dose: 28.7% average weight loss (~71 lbs / 32 kg) 9mg dose: 26.4% average weight loss (~64 lbs / 29 kg) Knee osteoarthritis pain: 76% reduction (significant quality-of-life improvement) Blood pressure: Average reduction of 14 mmHg Full Phase 3 results across the TRIUMPH program (obesity, diabetes, cardiovascular outcomes, kidney outcomes) are expected throughout 2026

These findings suggested that our peptide exhibited potent functionality within cells as a senolytic drug with selectivity for senescent cells

doi: 10.1056/NEJMoa1411892 124 ButlerAEJansonJBonner-WeirSRitzelRRizzaRAButlerPC