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These nano-vesicles facilitate intercellular communication through autocrine, paracrine, and endocrine mechanisms by shuttling ncRNAs, including functional miRNAs and mRNAs

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This complex comprising TRF1, TRF2, POT1, TPP1, TIN2, and RAP1 serves a dual function: it protects chromosomal ends from being recognized as double-strand breaks by the DNA damage response machinery, and it regulates telomerase access to the telomere overhang

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