In terms of mechanism, DNA damage repair is the most critical reason for the radiotherapy resistance of GH and IGF1 in cancer cells and damage repair effect on adjacent tissues
The body naturally produces glutathione, but its levels can decrease due to: - Aging - Stress - Poor diet - Smoking - Environmental pollution - Lack of sleep - Chronic illness - Excessive sun exposure When glutathione levels decline, the skin may appear dull, tired, uneven, and more prone to pigmentation issues
Its pathogenesis is related to genetics, oxidative stress, lipid metabolism disorders, hemodynamic abnormalities, inflammatory responses, cell apoptosis, and renal fibrosis (Flemming et al., 2018)
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