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In OC treatment, the natural compound -sitosterol (SIT) has demonstrated the potential to strengthen the interaction between NRF2 and Keap1, promoting NRF2s ubiquitin-dependent degradation and subsequently diminishing the transcriptional activation of downstream antioxidant genes

Swirl the vial gently until the powder is fully dissolved

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Conservative approaches encompass oral therapy with colchicine, potassium para -aminobenzoate, tamoxifen, antioxidants, phosphodiesterase-5 inhibitors, and so on

doi: 10.1159/000501081 55 VermaSMcMurrayJJV