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Comprehensive toxicology evaluations reveal that the compound does not affect food intake, body temperature regulation, or basic physiological parameters at effective doses in animal models, indicating that its metabolic effects occur through specific pathway modulation rather than general physiological disruption
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Emerging studies using CSF and advanced neuroimaging techniques, such as brain magnetic resonance spectroscopy (MRS) are beginning to uncover neurobiological changes that may further elucidate disease mechanisms
