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Research interest in the arginine salt variant has grown because of its potentially improved water solubility and shelf stability compared to the standard form, though both variants appear in the preclinical literature and researchers continue to examine how these formulation differences may affect biological activity

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The goal is to find the highest dose you can tolerate comfortably, not to reach the maximum dose as quickly as possible

To be considered, requests for NTIOL reviews must include information requested on the CMS website at:

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