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This technology originated in the 1970s, was initially used to study the interactions between proteins and small molecules, and has now expanded to complex systems such as protein-protein and nucleic acid-ligand interactions, even applicable to larger molecules like short peptides and macrocyclic compounds (Porter et al., 2019

doi: 10.1111/1751-7915.13779 86 LitvakY.ByndlossM

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10.3389/fcell.2021.807862 151 WangL.ChenX.YanC