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If you are a vegetarian or vegan, knowing that you are at risk for B12 deficiency is essential

First, if you have proven deficiency under NHS care and want a private top-up injection between NHS doses because your symptoms return early, we will do that on agreed protocol after seeing your blood results

It is a biologically active fraction of vitamin B 12 that can be readily taken up by all cells and represents only 6% to 20% of total serum vitamin B 12 .23 In vitamin B 12 deficiency, serum level of holotranscobalamin decreases even before elevation in homocysteine and MMA levels occurs.24 It has been shown that holotranscobalamin is the most sensitive marker for vitamin B 12 deficiency, followed by MMA.23 25 Like homocysteine and MMA, holotranscobalamin cannot be tested in renal patients as its level increases in renal impairment.23 Furthermore, higher cost and lesser availability than homocysteine and MMA testing make it difficult to acquire wide clinical acceptance

Once the vitamin B12 reserves reach their normal levels, the injection of vitamin B12 will be needed as maintenance shot once every one to three months to prevent any of the symptoms of deficiency from returning

Link Innerbody Research Team

This reaction forms 1-methylnicotinamide (1-MNA) and S-adenosyl-L-homocysteine (SAH)