Key Takeaways: GLP-1 vs GIP Both are incretin hormones released by your intestines after eating GLP-1 primarily affects appetite, gastric emptying, and insulin secretion GIP influences insulin secretion, glucagon regulation, and fat metabolism Single GLP-1 agonists (semaglutide) produce 14.9% average weight loss Dual GLP-1/GIP agonists (tirzepatide) produce 22.5% average weight loss The dual action appears to create additive rather than merely overlapping effects Both receptor types play important roles in metabolic regulation Understanding the difference helps explain why tirzepatide shows superior results What Are Incretin Hormones
External resources SURMOUNT-4 Trial: Continued Treatment With Tirzepatide for Maintenance of Weight Reduction (JAMA) Cardiometabolic Parameter Change by Weight Regain on Tirzepatide Withdrawal (JAMA Internal Medicine) In case I do not see you, good afternoon, good evening, and good night
What is Wegovy and Saxenda
doi:10.1016/j.ejmg.2014.10.004 [4] Liew SC, Gupta ED
Exendin-4 Exhibits enhanced anti-tumor effects in diabetic mice
pediatric: 30 g/kg nightly) [1] [2]
