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This process primarily occurs in the liver, the bodys main organ for detoxification.[ref] The CYP450 enzymes have iron and oxygen in them and, through a redox reaction, can make a drug, toxin, or endogenous substance more polar

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Ensuring adequate intake of iron-rich foods (such as lean red meat, lentils, spinach, and fortified cereals) and vitamin B12 (found in meat, dairy, and eggs) can help prevent deficiencies that may worsen cold sensations

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