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In response to comments that our proposed approach risks circular and destabilizing effects across both FFS and MA and could create uncertainty within the MA program, FFS program, and value-based payment models that depend on a stable FFS baseline, we disagree

However, the risk increases meaningfully when retatrutide is used alongside insulin or sulphonylureas, and this combination requires careful clinical monitoring

J Am Chem Soc 139:1455614567

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Combining moderate physical activity with IF significantly reduced markers of inflammation while supporting antioxidant function [73]

Similarly, a significant difference in BMI was observed across nicotine craving categories