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Clinically Down syndrome is manifested by hypothyroidism, malformation of the cardiac system and gastrointestinal tract, abnormal hearing and vision, and aberrant development of the brain resulting in severe intellectual disability

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Results of the trial showed "Adolescent and adult patients with vitiligo achieved substantial facial and total body re-pigmentation within 24 to 52 weeks of therapy." Half of all participants had 75% improvement of their facial vitiligo after one year using the study's measurement of repigmentation

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