The insulin-like growth factor-I gene and osteoporosis: a critical appraisal
should be considered before using GLP-1
a , Uptake of [ 13 C 2 , 15 N]-GSH into mitochondria isolated from HEK-293T SLC25A39 knockout cells expressing a vector control, SLC25A39 cDNA, SLC25A10 (DIC, mitochondrial dicarboxylate carrier) or SLC25A11 (OGC, mitochondrial oxoglutarate carrier) cDNA at 5 s and 10 min
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Compared to GLP-1, the second residue of exenatide is Gly rather than Ala
Therefore, mutations in the PLPBP gene disrupt this process, causing PLP to react with other substrates and impacting the metabolism of important amine or amino acid neurotransmitters in the brain, consequently leading to the development of epilepsy