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Other long-term trials designed to evaluate whether SGLT2 inhibitors have renal protective effects in participants with T2D, and without T2D but with or without chronic kidney disease and macroalbuminuria are ongoing (e.g., the Evaluation of the Effects of Canagliflozin on Renal and Cardiovascular Outcomes in Participants With Diabetic Nephropathy (CREDENCE) study, NCT02065791

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104:234-239 [PubMed: 19576353] 90

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Temperatures above 30C (86F)such as in a warm car, sunny windowsill, or bathroom cabinet near a heat sourcecan degrade compounded semaglutide within 12 hours