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Zepbound Zepbound (tirzepatide) is an injectable medication that's used along with diet and exercise

Recent clinical interest has focused on whether GLP-1 receptor agonists like semaglutide might address the underlying appetite dysregulation in PWS patients

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A 2005 study demonstrated that both peptide and non-peptide GH secretagogues act through the GHS-R1a receptor but can also function as ghrelin receptor ligands with distinct binding properties, suggesting potential differences in downstream signaling despite shared receptor engagement