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39 Additionally, there is established evidence of alterations in glutamate circuits and GABAergic circuits in ASD patients, as manifested by increased numbers of excitatory synapses and spine densities, significantly reduced levels of glutamic acid decarboxylase, and GABAA and GABAB receptor alterations in the postmortem brains of patients with autism

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When a compound changes gene expression, it alters which proteins a cell produces potentially shifting the cell's behaviour toward repair, growth, or protection

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