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Semaglutide is a GLP-1 receptor agonist that mimics a natural hormone controlling hunger and blood sugar, helping patients lose an average of 15% of body weight over 68 weeks in clinical trials

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The mortality rate of rats in the PENs-induced AD groups within 30 min was over 75%, and the rats died within 18 min after challenged, while rats in the BSA group did not die within 30 min (see Supplementary Tab