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Toute perturbation de ce processus peut entraner un retard de cicatrisation, une fragilit cutane persistante ou encore des cicatrices hypertrophiques

they also function as physiological regulators in various cellular signalling pathways

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Endocrinology 155 , 2126 (2014)

Validating these findings, we show that deletion of the mitochondrial pyruvate carrier, which is known to decrease TCA cycle activity and protect the liver from diet-induced injury, also diminished NADPH, elevated glutathione oxidation, and alleviated ER stress