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11 Treatment targets The treatment targets in most patients with UC comprise: 12 clinical remission this short-term target to improve quality of life is conventionally defined as stool frequency of three or fewer daily and the absence of rectal bleeding 13 endoscopic healing this is defined by normalisation of vascular pattern, absence of mucosal friability, erosions and ulceration

The body requires vitamin B12 to maintain healthy nerve cells and to produce the myelin sheath that protects nerve fibres

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