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Observations in human trials reported that semaglutide effectively reduced body fat while maintaining muscle mass in obese T2D patients [165,166]

BMJ Open 8 , e023830 (2018)

It addresses the constellation of metabolic risk factors collectively known as metabolic syndrome, which is the primary driver of cardiovascular disease, type 2 diabetes, and premature death in patients with obesity

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In addition, glucagon like peptide-1 receptor agonists (GLP-1RAs) can be combined with GLP-1Rs, playing the same role as GLP-1

Ozempic is also sometimes prescribed off-label (for a non-FDA-approved use) as a weight loss drug