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It is important to understand the circumstances in which prompt medical advice should be sought both for trial participants and for healthcare professionals monitoring patients

To evaluate the incidence of MACE-4 events in patients treated with tirzepatide compared to the control group, a meta-analysis was conducted using data from 7778 patients enrolled in the SURPASS-4 study, SURPASS Clinical Trails Program (which includes 7 randomized clinical trials), and SURMOUNT-1

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All compounds were prepared as solutions in isotonic saline and dosed as s.c