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Jackowska, M., et al

In 56-week clinical trials, patients taking Contrave with diet and exercise lost an average of 5-9% of their body weight, compared to 1-5% with placebo

They stimulate insulin secretion from pancreatic beta cells in a glucose-dependent manner, meaning insulin is released only when blood glucose levels are elevated

Effect of tirzepatide versus insulin degludec on liver fat content and abdominal adipose tissue in people with type 2 diabetes (SURPASS-3 MRI): A substudy of the randomised, open-label, parallel-group, phase 3 SURPASS-3 trial

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