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Lixisenatide, a drug developed to treat type 2 diabetes, shows neuroprotective effects in a mouse model of Alzheimers disease
Autophagy and macrophage functions: inflammatory response and phagocytosis
In 2021, the FDA approved Novo Nordisk's Wegovy, a slight reformulation of Ozempic designed specifically for weight loss, which drove a huge spike in public awareness of GLP-1 agonists
503A compounding pharmacies compound according to specific patient prescriptions and are required by state boards of pharmacy to comply with standards. Because of the popularity and high demand of GLP-1 medications, Mir Ali, MD, bariatric surgeon and medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in Fountain Valley, CA, worried this may drive some people to purchase their medication through a potentially unsafe option
The median duration of GLP-1RA use was 21 months (IQR: 1531), and the median duration of insulin use was 23 months (IQR: 1538)
These medications should also be avoided in anyone with multiple endocrine neoplasia syndrome type 2 due to increased risk
