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Eryptosis is a type of regulated cell death of mature erythrocytes critically dependent on Ca 2+ signaling and linked with cell shrinkage, membrane blebbing, and phosphatidylserine externalization

To ultimately tease apart any possible cause from secondary events, species-specific biology will also need to be carefully dissected and interpreted

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In the blood pressure maintenance experiment, NaBPC157 was given intravenously (i.v.)

As expected, BSA-PC reduced the phosphorylation of GSK-3 at S9 in SH-SY5Y cells compared to those treated with BSA alone, without altering native GSK-3 protein levels (Fig 5A and 5B)

Authors' contributions: JS and DF participated in the conception and design of the review, revised the whole manuscript, and read and approved the final manuscript