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Adaptational modification of serine and threonine metabolism in the liver to essential amino acid deficiency in rats

They work through complementary but different mechanisms

Understanding these factors can help explain individual variations in metabolic health and glucose regulation

The secondary outcomes were all-cause death, heart failure admission, admission due to any cause, composite major adverse limb events including newly diagnosed peripheral arterial disease, claudication, clinical limb ischemia, limb revascularization or amputation, hypoglycemia, diabetic ketoacidosis (DKA) or hyperosmolar hyperglycemic state (HHS), and infection death