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Other implicated genes are Clusterin (CLU) , Sortilin-related receptor-1 (SORL1) , ATP-binding cassette subfamily A member 7 (ABCA7) , Bridging integrator 1 (BIN1) , phosphatidylinositol binding clathrin assembly protein (PICALM) , CD2 associated protein (CD2AP) , Complement component (3b/4b) receptor 1 (CR1) , CD33, triggering receptor expressed on myeloid cells 2 (TREM2) , and phospholipase D3 (PLD3) (Karch and Goate, 2015)

Though findings from animal models provide an important basis for future research in humans, the findings from studies using animal models need to be interpreted with caution and as hypothesis generating, rather than definitive evidence of the neuroprotective effects of RT

Sun K, Tordjman J, Clement K, Scherer PE

Journal of Neuroscience 20, 660-665CrossRefGoogle Scholar 138Nagai, M., Re, D.B., Nagata, T

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These cells can be isolated from a wide range of tissues, such as bone marrow, adipose tissue, dental pulp, umbilical cord, blood, placenta, hair, synovial fluid, liver, and heart [25,26,27,28,29,30]