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( Epub 2022/03/10 )

Treatment Options for Anal Fissures Most fissures heal on their own within a few weeks with simple home care and lifestyle adjustments

B12 supplementation in elderly patients with confirmed deficiency typically takes two main forms in the UK: Oral tablets (cyanocobalamin) Intramuscular injections (hydroxocobalamin, the standard form in the UK) NICE Clinical Knowledge Summary guidance recommends investigating B12 deficiency in older adults presenting with unexplained anaemia, neuropathy, cognitive impairment, or glossitis

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Proc Natl Acad Sci USA 108:1713517140 Hu H, Zhang H, Ge W, Liu X, Loera S, Chu P et al (2012) Secreted protein acidic and rich in cysteines-like 1 suppresses aggressiveness and predicts better survival in colorectal cancers

570 The amount of time required for caregiving increases as dementia progresses