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Education about the limitations of surgical diagnosis and the appropriateness of clinical diagnosis requires time and skill that many providers lack (Culley et al., 2017)

Although tumor radioresistance stands as a fundamental barrier limiting the effectiveness of radiation therapy, the exact molecular mechanisms underlying the radioadaptive response are largely unknown (Figure 4)

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Vigorous shaking can denature the peptide, meaning it can break the fragile bonds that give the molecule its specific shape and function

Biochem Biophys Res Commun 324 : 231235 Wong A, Yang J, Cavadini P, Gellera C, Lonnerdal B, Taroni F, Cortopassi G 1999 The Friedreich's ataxia mutation confers cellular sensitivity to oxidant stress which is rescued by chelators of iron and calcium and inhibitors of apoptosis